• About death

Death is the permanent end of the life of a biological organism. Death may refer to the end of life as either an event or condition. Many factors can cause or contribute to an organism's death, including predation, disease, habitat destruction, senescence, malnutrition and accidents. The principal causes of death in developed countries are diseases related to aging. Traditions and beliefs related to death are an important part of human culture, and central to many religions. In medicine, biological details and definitions of death have become increasingly complicated as technology advances.

N In medicine

Historically, attempts to define the exact moment of death have been problematic. Death was once defined as the cessation of heartbeat (cardiac arrest) and of breathing, but the development of CPR and prompt defibrillation have rendered the previous definition inadequate because breathing and heartbeat can sometimes be restarted. This is now called "clinical death". Events which were causally linked to death in the past no longer kill in all circumstances; without a functioning heart or lungs, life can sometimes be sustained with a combination of life support devices, organ transplants and artificial pacemakers.

Today, where a definition of the moment of death is required, doctors and coroners usually turn to "brain death" or "biological death": People are considered dead when the electrical activity in their brain ceases (cf. persistent vegetative state). It is presumed that a stoppage of electrical activity indicates the end of consciousness. However, suspension of consciousness must be permanent, and not transient, as occurs during sleep, and especially a coma. In the case of sleep, EEGs can easily tell the difference. Identifying the moment of death is important in cases of transplantation, as organs for transplant must be harvested as quickly as possible after the death of the body.

The possession of brain activity, or ability to resume brain activity, is a necessary condition to legal personhood in the United States. "It appears that once brain death has been determined ... no criminal or civil liability will result from disconnecting the life-support devices". (Dority v. Superior Court of San Bernardino County)

Those maintaining that only the neo-cortex of the brain is necessary for consciousness sometimes argue that only electrical activity there should be considered when defining death. Eventually it is possible that the criterion for death will be the permanent and irreversible loss of cognitive function, as evidenced by the death of the cerebral cortex. All hope of recovering human thought and personality is then gone. However, at present, in most places the more conservative definition of death — irreversible cessation of electrical activity in the whole brain, as opposed to just in the neo-cortex — has been adopted (for example the Uniform Determination Of Death Act in the United States). In 2005, the case of Terri Schiavo brought the question of brain death and artificial sustenance to the front of American politics.

Even by whole-brain criteria, the determination of brain death can be complicated. EEGs can detect spurious electrical impulses, while certain drugs, hypoglycemia, hypoxia, or hypothermia can suppress or even stop brain activity on a temporary basis. Because of this, hospitals have protocols for determining brain death involving EEGs at widely separated intervals under defined conditions.

N Misdiagnosed death

There are many anecdotal references to people being declared dead by physicians and then coming back to life, sometimes days later in their own coffin, or when embalming procedures are just about to begin. Owing to significant scientific advancements in the Victorian era, some people in Britain became obsessively worried about living after being declared dead.

A first responder is not authorized to pronounce a patient dead. Some EMT training manuals specifically state that a person is not to be assumed dead unless there are clear and obvious indications that death has occurred. These indications include mortal decapitation, rigor mortis (rigidity of the body), livor mortis (blood pooling in the part of the body at lowest elevation), decomposition, incineration, or other bodily damage that is clearly inconsistent with life. If there is any possibility of life and in the absence of a do not resuscitate (DNR) order, emergency workers are instructed to begin rescue and not end it until a patient has been brought to a hospital to be examined by a physician. This frequently leads to situation of a patient being pronounced dead on arrival (DOA). However, some states allow paramedics to pronounce death. This is usually based on specific criteria. Aside from the above mentioned conditions include advanced measures including CPR, intubation, IV access, and administering medicines without regaining a pulse for at least 20 minutes.

In cases of electrocution, CPR for an hour or longer can allow stunned nerves to recover, allowing an apparently-dead person to survive. People found unconscious under icy water may survive if their faces are kept continuously cold until they arrive at an emergency room. This "diving response", in which metabolic activity and oxygen requirements are minimal, is something humans share with cetaceans called the mammalian diving reflex.

As medical technologies advance, ideas about when death occurs may have to be re-evaluated in light of the ability to restore a person to vitality after longer periods of apparent death (as happened when CPR and defibrillation showed that cessation of heartbeat is inadequate as a decisive indicator of death). The lack of electrical brain activity may not be enough to consider someone scientifically dead. Therefore, the concept of information theoretical death has been suggested as a better means of defining when true death actually occurs, though the concept has few practical applications outside of the field of cryonics.

There have been some scientific attempts to bring dead organisms back to life, but with limited success. In science fiction scenarios where such technology is readily available, real death is distinguished from reversible death.

N Causes of human death

Death can be caused by disease, accident, homicide, or suicide. The leading cause of death in developing countries is infectious disease. The leading causes of death in developed countries are atherosclerosis (heart disease and stroke), cancer, and other diseases related to obesity and aging. These conditions cause loss of homeostasis, leading to cardiac arrest, causing loss of oxygen and nutrient supply, causing irreversible deterioration of the brain and other tissues. With improved medical capability, dying has become a condition to be managed. Home deaths, once the norm, are now rare in the first world.

In third world countries, inferior sanitary conditions and lack of access to medical technology makes death from infectious diseases more common than in developed countries. One such disease is tuberculosis, a bacterial disease which killed 1.7 million people in 2004.

Many leading first world causes of death can be postponed by diet and physical activity, but the accelerating incidence of disease with age still imposes limits on human longevity. The evolutionary cause of aging is, at best, only just beginning to be understood. It has been suggested that direct intervention in the aging process may now be the most effective intervention against major causes of death.

N Life extension

Life extension refers to an increase in maximum or average lifespan, especially in humans, by slowing down or reversing the processes of aging. Average lifespan is determined by vulnerability to accidents and age-related afflictions such as cancer or cardiovascular disease. Extension of average lifespan can be achieved by good diet, exercise and avoidance of hazards such as smoking and excessive eating of sugar-containing foods. Maximum lifespan is determined by the rate of aging for a species inherent in its genes. Currently, the only widely recognized method of extending maximum lifespan is calorie restriction. Theoretically, extension of maximum lifespan can be achieved by reducing the rate of aging damage, by periodic replacement of damaged tissues, or by molecular repair or rejuvenation of deteriorated cells and tissues.

Researchers of life extension are a subclass of biogerontologists known as "biomedical gerontologists". They seek to understand the nature of aging and they develop treatments to reverse aging processes or to at least slow them down, for the improvement of health and the maintenance of youthful vigor at every stage of life. Those who take advantage of life extension findings and seek to apply them upon themselves are called "life extensionists" or "longeviusts". The primary life extension strategy currently is to apply available anti-aging methods in the hope of living long enough to benefit from a complete cure to aging once it is developed, which given the rapidly advancing state of biogenetic and general medical technology, could conceivably occur within the lifetimes of people living today.

Many biomedical gerontologists and life extensionists believe that future breakthroughs in tissue rejuvenation with stem cells, organs replacement (with artificial organs or xenotransplantations) and molecular repair will eliminate all aging and disease as well as allow for complete rejuvenation to a youthful condition. Whether such breakthroughs can occur within the next few decades is impossible to predict. Some life extensionists arrange to be cryonically preserved upon legal death so that they can await the time when future medicine can eliminate disease, rejuvenate them to a lasting youthful condition and repair damage caused by the cryonics process. Whether the maximum human lifespan should be extended is the subject of much ethical debate amongst politicians and scientists.

N Philosophy, religion and mythology

Faith in some form of afterlife is an important aspect of many people's beliefs. Such beliefs are usually manifested as part of a religion, as they pertain to phenomena beyond the ordinary experience of the natural world. For example, one aspect of Hinduism involves belief in a continuing cycle of birth, life, death and rebirth (Samsara) and the liberation from the cycle (Moksha). Eternal return is a non-religious concept proposing an infinitely recurring cyclic universe, which relates to the subject of the afterlife and the nature of consciousness and time. Though various evidence has been advanced in attempts to demonstrate the reality of an afterlife, these claims have never been validated. For this reason, the material or metaphysical existence of an afterlife remains a matter outside the scope of science.

Many cultures have incorporated a god of death into their mythology or religion. As death, along with birth, is among the major parts of human life, these deities may often be one of the most important deities of a religion. In some religions with a single powerful deity as the source of worship, the death deity is an antagonistic deity against which the primary deity struggles.

In polytheistic religions or mythologies which have a complex system of deities governing various natural phenomena and aspects of human life, it is common to have a deity who is assigned the function of presiding over death. The inclusion of such a "departmental" deity of death in a religion's pantheon is not necessarily the same as the glorification of death which is commonly condemned by the use of the term "death-worship" in modern political rhetoric. In the theology of monotheistic religion, the one god governs both life and death. However, in practice this manifests in different rituals and traditions and varies according to a number of factors including geography, politics, traditions and the influence of other religions.

N Personification of death

Death has been personified as a figure or fictional character in mythology and popular culture since the earliest days of storytelling. Because the reality of death has had a substantial influence on the human psyche and the development of civilization as a whole, the personification of Death as a living, sentient entity is a concept that has existed in many societies since the beginning of recorded history. In western culture, death is usually shown as a skeletal figure carrying a large scythe, and sometimes wearing a midnight black gown with a hood.

Examples of death personified are:

• in modern-day European-based folklore, Death is known as the "Grim Reaper" or "The grim spectre of death". This form typically yields a scythe, and is sometimes portrayed riding a white horse;
• in the Middle Ages, Death was imagined as a decaying or mummified human corpse, later becoming the familiar skeleton in a robe;
• death is sometimes portrayed in fiction and occultism as Azrael, the angel of death (note that the name "Azrael" does not appear in any versions of either the Bible or the Qur'an);
• father Time is sometimes said to be Death;
• a psychopomp is a spirit, deity, or other being whose task is to conduct the souls of the recently dead into the afterlife.

N The number 4 in East Asia

In China, Japan, and Korea the number 4 is often associated with death because the sound of the Chinese, Japanese, and Korean words for four and death are similar. For this reason, hospitals and hotels often omit the 4th, 14th, 24th, floors (etc.), or substitute the number '4' with the letter 'F'. Koreans are buried under a mound standing vertical in coffins made from six planks of wood. Four of the planks represent their respective four cardinal points of the compass, while a fifth represents sky and the sixth represents earth. This relates back to the importance that the Confucian society placed upon the four cardinal points having mystical powers.

N Glorification of and fascination with death

Whether because of its very poetic nature or because of the great mystery it presents, or both, death is and has very often been glorified in many cultures through many different means. War, crime, revenge, martyrdom, suicide and many other forms of violence involving death are often glorified by different media, often in modern times being glorified even in spite of the attempts at depicting death meant to be de-glorifying. For example, film critic Roger Ebert mentions in a number of articles that Francis Truffaut makes the claim it's impossible to make an anti-war film, as any depiction of war ends up glorifying it. The most prevalent and permanent form of death's glorification is through artistic expression. Through song, such as "Knockin' on Heaven's Door" or "Bullet in the Head", many artists show death through poetic analogy or even as a poetic analogy, as in the latter mentioned song. Events such as The Charge of the Light Brigade and The Battle of the Alamo have served as inspirations for artistic depictions of and myths regarding death.

Perception of glory in death is subjective and can even differ wildly from one member of a group to another. Religion plays a key role, especially in terms of expectations of an afterlife. Personal and perceptions about mode of death are also important factors. One person's martyr could be another person's waste of life.

Source: Wikipedia

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